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Cryo-transmission electron microscopy
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Description
Cryo-TEM analysis of colloidal particles involving vitrification of samples on holey carbon grids followed by high-resolution imaging at cryogenic temperatures to preserve native morphology.
Typical Equipment
- Quantifoil holey carbon TEM grids
- Thermo Fisher Vitrobot
- Thermo Fisher Titan Krios G3 TEM
- K3 direct-detection camera
Output Measurements
- particle morphology
- size distributions
- structural preservation